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Drug & Alcohol Rehab Centers in Santa Ana, California

Discover 15 addiction treatment facilities in Santa Ana. Our comprehensive directory helps you find the right rehabilitation center with 24/7 support available, licensed facilities, and insurance accepted at most locations. Whether you need detox services, residential treatment, outpatient programs, or sober living arrangements, find the perfect match for your recovery journey.

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Showing 15 of 15 results

Cornerstone Adult Outpatient
+9 photos
1950 East 17th Street, 92705
714-547-4300
Cornerstone Adult Outpatient in Santa Ana, CA provides comprehensive substance use treatment through multiple evidence-based modalities including cognitive behavioral therapy, motivational interviewing, and relapse prevention. The facility specializes in serving diverse populations including active duty military, individuals with co-occurring mental health and pain disorders, and criminal justice clients. With Joint Commission accreditation and state oversight, Cornerstone delivers flexible care ranging from intensive outpatient to medication-assisted treatment options.
Substance use treatment
Newport Academy
+9 photos
9951 Highcliff Drive, 92705
877-820-6371
Newport Academy in Santa Ana provides comprehensive substance use treatment and co-occurring mental health services for adolescents and adults. Specializing in evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling, the facility offers flexible care levels from intensive outpatient to 24-hour residential programs. With particular expertise serving LGBTQ individuals and trauma survivors, Newport Academy combines clinical excellence with culturally competent, person-centered treatment.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Newport Institute
+9 photos
12822 Periwinkle Drive, 92705
855-272-7451
Newport Institute in Santa Ana, CA specializes in comprehensive substance use and co-occurring mental health treatment for adolescents, young adults, and adults. The facility offers evidence-based approaches including cognitive behavioral therapy, trauma-focused counseling, and anger management across multiple settings from intensive outpatient to 24-hour residential care. With Joint Commission accreditation and specialized programming for LGBTQ+ individuals and trauma survivors, Newport Institute delivers personalized recovery pathways tailored to each client's unique needs.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Newport Institute
+9 photos
9881 Deerhaven Drive, 92705
855-272-7451
Newport Institute in Santa Ana, CA specializes in comprehensive substance use and co-occurring mental health treatment for adults and children. The facility offers evidence-based therapies including cognitive behavioral therapy, trauma counseling, and relapse prevention across multiple levels of care—from intensive outpatient programs to 24-hour residential treatment. Accredited by The Joint Commission, Newport Institute is known for serving LGBTQ+ individuals and young adults with personalized, compassionate recovery pathways.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Newport Institute
+9 photos
10022 Miramar Circle, 92705
855-272-7451
Newport Institute in Santa Ana, CA provides comprehensive substance use and co-occurring mental health treatment for adults and children through multiple evidence-based modalities. Their programs span from intensive outpatient care to long-term residential treatment, utilizing cognitive behavioral therapy, motivational interviewing, and trauma-informed approaches. The facility is particularly recognized for specialized programming serving LGBTQ individuals, young adults, and those with complex trauma histories.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Pacific Sands Recovery Center
+9 photos
1909 West Carlton Place, 92704
844-568-7328
Pacific Sands Recovery Center in Santa Ana provides comprehensive detoxification and substance use treatment in a hospital inpatient setting, specializing in co-occurring mental health and substance use disorders. The center offers evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and trauma-informed care, serving diverse populations including veterans, LGBTQ individuals, and survivors of abuse. Their Joint Commission accreditation and state licensure ensure highest standards of care.
DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Phoenix House
+9 photos
Phoenix House

Orange County

1207 East Fruit Street, 92701
714-953-9373
Phoenix House in Santa Ana offers comprehensive substance use treatment and detoxification services for individuals with co-occurring mental health challenges. Specializing in evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and trauma-informed care, the facility serves diverse populations including LGBTQ+ individuals, veterans, and pregnant women. With both residential and intensive outpatient options, Phoenix House provides flexible care pathways for lasting recovery.
DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Recovery Homes of America Inc
+9 photos
1950 East 17th Street, 92705
714-567-5345
Recovery Homes of America Inc in Santa Ana provides comprehensive substance use treatment through evidence-based outpatient and intensive programs tailored for diverse populations, including active duty military and individuals with co-occurring mental health or chronic pain conditions. The facility specializes in multiple therapeutic approaches such as cognitive behavioral therapy, motivational interviewing, and 12-step facilitation, with flexible delivery options including telemedicine to increase accessibility. Accredited by The Joint Commission and state health agencies, the center serves as a trusted resource for those seeking recovery in Orange County.
Substance use treatment
Santa Ana Comprehensive Treatment Ctr
+9 photos
Santa Ana Comprehensive Treatment Ctr

California Treatment Services LLC

2101 East 1st Street, 92705
714-581-9181
Santa Ana Comprehensive Treatment Center in Santa Ana, CA offers specialized detoxification and substance use disorder treatment through evidence-based outpatient and medication-assisted programs. The center provides tailored care for diverse populations including veterans, LGBTQ+ individuals, trauma survivors, and those with co-occurring mental health conditions. With CARF accreditation and SAMHSA certification, they deliver compassionate, clinically rigorous treatment designed for sustainable recovery.
DetoxificationSubstance use treatment
Orange County Healthcare Agency
+4 photos
Orange County Healthcare Agency

Behavioral Health Services/SUD

401 West Civic Center Drive, 92701
714-834-3840
Orange County Healthcare Agency in Santa Ana provides comprehensive substance use treatment with specialized programs for adults, pregnant women, and trauma survivors. Using evidence-based approaches like cognitive behavioral therapy, motivational interviewing, and relapse prevention, they address co-occurring mental health and substance use disorders. Their flexible care options range from intensive outpatient treatment to medication-assisted therapy with methadone, buprenorphine, and naltrexone.
Substance use treatment
Orange County Healthcare Agency
+4 photos
Orange County Healthcare Agency

Drug Court and DUI Programs

401 West Civic Center Drive, 92701
714-480-6650
Orange County Healthcare Agency in Santa Ana provides comprehensive substance use treatment through evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-informed care. As a state-accredited substance use treatment agency, they offer flexible care options ranging from intensive outpatient programs to medication-assisted treatment with methadone, buprenorphine, and naltrexone. Their integrated approach addresses co-occurring issues like anger management and relapse prevention while leveraging telehealth to increase accessibility.
Substance use treatment
PES/EBS Inc
600 West Santa Ana Boulevard, 92701
530-888-1010
PES/EBS Inc in Santa Ana provides comprehensive substance use treatment through evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-informed care. Serving criminal justice-involved clients, this state-accredited facility offers flexible care levels from regular outpatient to intensive programs, with medication-assisted treatment options including methadone and buprenorphine.
Substance use treatment
Cooper Fellowship Inc - Placeholder
409 North Cooper Street, 92703
714-554-1152
Cooper Fellowship Inc in Santa Ana, CA provides comprehensive long-term residential substance use treatment with a trauma-informed approach. Specializing in serving diverse populations including veterans, military families, LGBTQ individuals, and survivors of abuse, the facility employs evidence-based therapies such as cognitive behavioral therapy, Matrix Model, and community reinforcement strategies. Their 24-hour residential setting ensures intensive support for clients managing co-occurring mental health, pain conditions, and substance use disorders.
Substance use treatment
Straight Talk Clinics Inc - Placeholder
1225 West 6th Street, 92703
714-972-1402
Straight Talk Clinics Inc in Santa Ana, CA provides comprehensive substance use treatment through evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and the Matrix Model. The facility operates residential treatment programs (short-term and long-term) with specialized support for diverse populations including LGBTQ individuals, veterans, trauma survivors, and those with co-occurring mental health or pain disorders. Accredited by state health authorities, Straight Talk combines 12-step facilitation with contingency management and telemedicine options for flexible recovery pathways.
Substance use treatment
Villa Center Inc - Placeholder
910 North French Street, 92701
714-541-2732
Villa Center Inc in Santa Ana provides comprehensive substance use treatment through long-term and short-term residential programs designed for diverse populations including veterans, military families, and survivors of trauma or domestic violence. The facility specializes in evidence-based approaches such as cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling, with particular expertise serving LGBTQ individuals, pregnant women, and clients with co-occurring mental health disorders. State-accredited and multi-departmentally licensed, Villa Center offers personalized recovery pathways that address the unique needs of each client.
Substance use treatment

Addiction Treatment in Santa Ana

Santa Ana is home to a diverse range of addiction treatment facilities, offering comprehensive care for individuals struggling with substance abuse and co-occurring mental health disorders. Whether you're a resident of Santa Ana or traveling for treatment, you'll find quality rehabilitation centers that can help you begin your recovery journey.

Why Choose Treatment in Santa Ana?

  • Accessibility: Multiple treatment centers throughout the city with various specializations
  • Quality Care: Licensed and accredited facilities with experienced professionals
  • Diverse Options: From luxury rehabs to affordable state-funded programs
  • Support Network: Strong recovery community with numerous support groups
  • Continuum of Care: Full spectrum from detox to aftercare services

Types of Programs Available

Treatment centers in Santa Ana offer various levels of care to meet different needs:

  • Medical Detox: Safe, supervised withdrawal management
  • Inpatient/Residential: 24/7 care in a structured environment
  • Partial Hospitalization (PHP): Intensive day treatment programs
  • Intensive Outpatient (IOP): Flexible scheduling for working professionals
  • Standard Outpatient: Weekly therapy and support groups
  • Sober Living: Transitional housing for ongoing recovery support

Getting Started with Treatment

Finding the right treatment center in Santa Ana starts with understanding your specific needs. Consider factors such as the type of substance use, any co-occurring mental health conditions, insurance coverage, and personal preferences for treatment approach. Many facilities offer free consultations to help you determine the right fit for your recovery journey.